Intraoperative · GDP Rescue

Transfusion-to-Target

Real-time pRBC dosing · Cannula ceiling analysis · Swap scenario planning

Shackelford · MUSC Perfusion Services

Clinical Purpose

When on-bypass Hct is insufficient to achieve the GDP flow target (300 mlO₂/min/m²), this tool calculates the precise pRBC units needed to reach target — preventing over-transfusion. Activate the Cannula Rescue Protocol below to add hardware ceiling analysis and swap scenario planning.

pRBC: Hct 60%, 300 mL/unit · GDP: 300 mlO₂/min/m² · PaO₂ 150 mmHg

1Patient

2Circuit Setup

Crystalloid fraction only

3Intraoperative Status

Saline, heparin flushes, etc.

0.7 mL/kg/hr
0.3 minimalDefault 0.71.5 high

Literature range 0.5–1.0 mL/kg/hr for open cardiac surgery.

🚨 Cannula Rescue Protocol

Tap to activate cannula ceiling & swap scenario analysis